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Directions from St. Louis, Carbondale, Cairo or Harrisburg via I-55 North:

Traveling on I-55 North, take Exit 92A-B/6^th Street/I-55-Bl North/Jacksonville (US-36 W). Continue for approx. 3.5 miles on 6^th Street and South 6^th Street. Turn left on South Grand Avenue East/Illinois Route 54 and travel for 0.3 miles. Turn right on South Second Street and travel for 0.4 miles. Diocesan Center is on the left side.

Directions from Chicago, Bloomington or Normal via I-55 South:

Traveling on I-55 South, take Exit 98B/Clear Lake Avenue/IL 97-West. Continue for 3.3 miles on IL-97-West. Turn left on North Second Street and travel for 0.1 mile. Continue on South Second Street and travel for 0.6 miles. Diocesan Center is on the right side.

Directions from Jacksonville via I-72 East:

Traveling on I-72 East (US-36), take Exit 97B/6^th Street/I-55-Bl North-towards Springfield. Continue for approx. 3.5 miles on 6^th Street and S 6^th Street. Turn left on South Grand Avenue East/Illinois Route 54 and travel for 0.3 miles. Turn right on South Second Street and travel for 0.4 miles. Diocesan Center is on the left side.

Directions from Champaign, Danville or Robinson via I-72 West: